Frankie Bell (Claire van der Boom) takes on the system to save a patient, and lands in trouble. Lou Tannis (Andrea Demetriades) finds out it’s not always wise to have an affair with a boss, and Tabb (Arka Das) questions his ability as a doctor. Frankie learns that her mentor, Chad Berger (Owen Teale), is as vulnerable as any one.
Frankie (Claire van der Boom) comforts a nervous Zoe (Melissa Bonne) in the lead up to her heart transplant, while also dealing with rebellious teen Kelly (Selena Milinkovic), who had a kidney transplant but has been lying about taking her medication.
Tabb (Arka Das) takes on Samoan outlier patient Abe (Ray Chong Nee), but after connecting with him on a deep level, Tabb loses him and questions his own ability as a doctor.
Zoe (Melissa Bonne) goes in for her heart transplant. But tensions rise in the theatre as personal politics interfere. Lou (Andrea Demetriades) calls stop, claiming to have seen Mitri (Blessing Mokgohloa) miss a stitch, but he doesn’t listen, closing Zoe up.
Frankie saves Kelly’s life, and finally gets through to the frightened teenager: this second chance at life is precious, and neither of them can afford to forget that. In an intimate moment, Berger (Owen Teale) reveals he has his own health issues. As they share a bottle of wine, Frankie is faced with the question: will she be able to save the man who saved her?